IgA Nephritis--Ace inhibitors, steroids etc?
نویسندگان
چکیده
منابع مشابه
ACE Gene Polymorphism and renal responsiveness to ACE inhibitors in IgA nephropathy patients
We examined the renal responsiveness to ACE inhibitor in IgA nephropathy (IgAN) patients according to the grouping of ACE gene polymorphism. Sixty one patients diagnosed as IgAN by renal biopsy and prescribed with ACE inhibitors were enrolled. Genomic DNA was extracted from whole blood and PCR was performed. The I/D polymorphism was determined by the presence of the 287 bp fragment in intron 16...
متن کاملACE, ACE inhibitors, and other JNK.
The renin-angiotensin system (RAS) plays a pivotal role in the regulation of blood pressure, volume homeostasis, vascular function, and cell growth. In what is considered the classic RAS, renin is released from juxtaglomerular cells of the kidney into the circulation where it converts angiotensinogen from the liver to angiotensin I. Angiotensin I is subsequently hydrolyzed by a peptidyl dipepti...
متن کاملTreatment of IgA nephropathy with ACE inhibitors: a randomized and controlled trial.
Some retrospective studies have suggested a beneficial influence of angiotensin-converting enzyme (ACE) inhibitors on the progression of IgA nephropathy (IgAN), but prospective and controlled studies demonstrating this effect are lacking. Forty-four patients with biopsy-proven IgAN, proteinuria > or = 0.5 g/d, and serum creatinine (SCr) < or = 1.5 mg/dl were randomly assigned either to receive ...
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I mmunoglobulin A nephropathy (IgAN) is the most prevalent form of primary glomerulonephritis and one of the principal causes of end stage renal disease (ESRD) throughout the world. 2 It is a complex disease, in which familial clustering suggests an inherited genetic predisposition. The disease has a variable clinical course, and one third of patients with IgAN progress to ESRD within 10–20 yea...
متن کاملACE inhibitors and anaesthesia.
During the last decade, two angiotensin converting enzyme (ACE) inhibitors, captopril and enalapril, have become accepted into clinical practice and are regarded as effective treatments for hypertension and congestive cardiac failure.' A third agent, lisinopril, had recently become available and others are likely to be introduced in the near future. It is clear, therefore, that more patients, w...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2007
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/gfm069